Bedaquiline- and clofazimine-resistant Mycobacterium tuberuclosis reference strains available in public collection of mycobacterial strains BCCM/ITM


The global burden of multi-drug tuberculosis (MDR-TB) was estimated  in 2013 at  5.3% of TB cases, including  9% with extensively drug-resistant tuberculosis (XDR-TB)1.  Only 48% of MDR cases were treated successfully, in part due to high toxicity, the long duration of the current regimens, and drug supply interruptions. To overcome these constraints, new TB drugs were deemed essential  and have been  developed, yet their safety and efficacy are being assessed in Phase II and III clinical trials for patients with MDR-TB.

Biological control agents: from field to market, problems, and challenges


New publication by Siva L.S. Velivelli, Paul De Vos, Peter Kromann,Stephane Declerck, Barbara D. Prestwich in Trends in Biotechnology

This article focuses on the problems and challenges encountered when introducing biological control agents on the market. The role that culture collections, such as the BCCM collections, can play in this process is described.


BCCM/IHEM organises a course on fungi of the environment from 29 September until 3 October 2014


From the 29th of September until the 3th of October, training in Mycology is organised at BCCM/IHEM. This one week training is focusing on Fungi of the human environment and includes a theoretical part as well as practical training in the laboratory.

Interested in such a training? Need more details?
Please contact us at



Human ORFeome v8.1 available at LMBP - over 12.000 human genes in Gateway Entry vectors


The hORFv8.1 database consists of a sequence-verified, clonal collection of human Open Reading Frames (ORFs), presented as Gateway Entry vectors (backbone: pDONR223).  All clones come without a termination codon, allowing the addition of C-terminal tags or markers.

BCCM/LMBP provides this large collection as individual plasmids, and offers a range of compatible Gateway Destination vectors, aiming to satisfy your imagination for your experimental set-ups.

See the BCCM/LMBP ORFeome v8.1 entry plasmids catalogue here.

Toolkit for rapid and efficient generation of transgenic mice: RMCE-compatible plasmids + G4 ROSALUC mouse ES cells


Prof. Jody Haig's research group (IRC, VIB, Ghent, Belgium) developed a highly efficient Gateway- and recombinase-mediated cassette exchange (RMCE)-compatible system to target conditional and/or inducible constructs to the ROSA26 locus of F1 hybrid Bl6/129 ESCs, called G4 ROSALUC ES cells.
This technology allows researchers to easily create conditional and/or inducible ROSA26 alleles in a time/cost efficient manner.