A series of 52 deletion mutant strains of Saccharomyces cerevisiae with increased sensitivity to numerous toxic compounds, including antifungals used in agriculture and medicine is available from BCCM/MUCL. These strains result from the systematic knockout analysis of multidrug efflux genes.
The antifungal resistance of clinical strains is routinely tested by clinical and reference laboratories using broth microdilutions or commercial tests. Professionals that want to analyse non-clinical strains (from research, industry, veterinary settings, etc.) can find a certified partner in BCCM/IHEM.
MICROMETABOLITE aims at exploring the plant-associated microflora for improving the production of bioactive secondary plant metabolites of high value for industrial applications. The network will focus on members of the Boraginaceae plant family, which produce the naphtoquinones shikonin and alkannin derivatives (A/S).