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E. coli strains for glycoengineering

This suite of 11 E. coli strains was created by sequential deletion and/or addition of genes, aiming to increase expression of pneumococcal conjugate vaccines. All strains express a detoxified endotoxin, which is a concerning contaminant of therapeutics produced in bacterial cells. This set of strains was published in Kay et al. (2022).

 

Fylogenetic tree of the E. coli strains, after Kay et al. (2022).